Tech Stack

Description

You will execute yeast transformations, matings, next-generation sequencing, and cell sorting/analysis to support production of yeast libraries and interrogation of protein-protein interactions. You'll work collaboratively to execute tasks in multiple workflows, supporting our AlphaSeq platform for drug discovery and optimization.

Requirements

• Bachelor's degree in a relevant field with 2+ years of relevant postbaccalaureate laboratory experience in the biotechnology industry; or an equivalent combination of education and experience.
• Proficiency in standard molecular biology techniques, including DNA extractions, quantitative PCR, Gibson assembly, and fragment analysis.
• Experience with multi-parametric flow cytometry.
• Experience in a high-throughput screening or manufacturing environment.
• Experience working within LIMS/ELN.
• Strong work ethic, good organizational skills, team orientation, and exquisite attention to detail.
• Flexibility in day-to-day schedule and willingness to work outside of standard hours when necessary, including weekends.

Responsibilities

• Execute DNA library preparation and sequencing workflows for Oxford Nanopore Technologies and Illumina platforms.
• Perform cell sorting and flow cytometry.
• Perform yeast transformation and matings.
• Execute DNA library construction as assigned.
• Support development and optimization of standard operating procedures for existing and new experimental workflows.
• May contribute to project teams or execute project-related tasks.
• As requested, train new Research Associates.
• Develop foundational understanding of and executional expertise in Technical Operations methods.
• Perform other duties as assigned.