19h ago

Scientist, LNP Process and Development

Cambridge, MA

โœจ $110k-$150k / yearest.

full-timemidbiotech

๐Ÿ’ผ About This Role

You'll develop and scale-up lipid nanoparticle (LNP) formulations for nucleic acid delivery at a Flagship-backed biotech startup. Your work will directly improve the performance and manufacturability of gene therapies. This role bridges process development and early-stage R&D on next-generation LNP systems.

๐ŸŽฏ What You'll Do

  • Support LNP formulation and scale-up, including mixing and encapsulation efficiency.
  • Design experiments to improve LNP performance and manufacturability.
  • Collaborate with teams for characterization and evaluation of LNP formulations.
  • Assist with technology transfer and scale-up activities.

๐Ÿ“‹ Requirements

  • PhD in Chemical Engineering, Pharmaceutical Sciences, or Bioengineering with 3+ years industry experience.
  • Process development or scale-up experience with nanoparticle or LNP systems.
  • Experience with nucleic acid formulations (mRNA, DNA) preferred.
  • Familiarity with T-mixing and characterization techniques (DLS, encapsulation assays).

โœจ Nice to Have

  • Experience in formulation screening and optimization.
  • Knowledge of next-generation LNP systems.

๐ŸŽ Benefits & Perks

  • ๐Ÿ”ฌ Cutting-edge research on LNP formulation innovation
  • ๐Ÿค Collaborative science-driven culture
  • ๐Ÿ’ฐ Competitive compensation and benefits package

๐Ÿ“จ Hiring Process

Estimated timeline: 2-4 weeks ยท AI estimate

  1. 1Recruiter screenยท 30 min
  2. 2Technical phone screenยท 45 min
  3. 3On-site interviewsยท 4 hours
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