Tech Stack

Description

You will lead the histology team in developing and executing IHC/ISH/IF assays, support biobank activities, cross-train in molecular biology, and contribute to cross-functional teams to advance gene therapy programs.

Requirements

• Degree in Immunology, Bioengineering, Molecular Biology, Cell Biology, Pharmacology, Biochemistry or related field; Master’s degree with 2+ years, bachelor’s with 4+ years or PhD with 1+ years of experience
• Immunohistochemistry automated assay development
• In situ hybridization automated assay development
• Experience in design and execution of complex image analysis using Visiopharm software
• Experience/troubleshooting common histology techniques (microtomy, grossing, embedding, H&E staining, special stains, pathology/anatomy)
• Proficiency with automated slide scanning and digital slide inventory programs
• Familiarity with CAP/CLIA standards for pathology labs/experiments
• Molecular biology and/or ligand binding assay (ELISA) techniques
• Excellent data summary/presentation skills
• Prior experience with bioanalytical or biomarker assay development is strongly preferred
• Successfully demonstrated ability to work independently in designing, developing, and executing new assay methods
• Successfully demonstrated ability to conduct research with strong attention to detail and rigorously analyze and interpret data
• Ability to multi-task and support more than one project simultaneously
• Highly organized and motivated; strong analytical, organizational, and problem-solving skills
• Strong work ethic, flexibility, and cooperative can-do attitude
• Ability to work cooperatively in a team-based environment
• Strong communication skills (both written and oral)
• Understanding and knowledge of key scientific software programs (including Microsoft Office, JMP or Prism, Adobe Photoshop)

Responsibilities

• Independent method development of automated ISH/IHC/IF histology biomarker assays
• Independent sample testing design/execution/interpretation/reporting of diverse histology biomarker studies
• Visiopharm image analysis app development and execution
• Development of complex multiplex IF methodology
• Supporting internal biobank project by receiving/accessioning, distributing and maintaining samples/inventories
• Cross-training with and supporting molecular biology and ligand binding assay subject matter experts
• Effective data summary and presentation to project teams and externally
• Leadership including cross training BI team members in areas of expertise
• Integration/participation in cross functional teams
• Leading and supporting research initiatives such as new technology development and platform improvement projects
• Writing study reports and manuscripts and presenting results at scientific meetings
• Maintaining compliance with company Environmental Health and Safety policies, procedures, and practices
• Contributing to building a culture that embraces continuous learning, improvement, and innovation