15h ago

Scientist - Structural Informatics Infrastructure

Emeryville HQ

$100k-$180k / year

full-timeleadbiotech

💼 About This Role

You'll lead the development of standards and platforms for a dynamic structural biology database, working at the intersection of structural biology, data science, and community standards. Your core impact will be building an ensemble-aware, living database that makes dynamic structural biology data as accessible and trustworthy as the PDB. This role stands out for operating at a high-velocity, startup-like research foundation.

🎯 What You'll Do

  • Lead conceptual design of ensemble-aware database architecture
  • Identify and prioritize technical challenges from data to query interfaces
  • Direct infrastructure enabling continuous model improvement with provenance
  • Oversee ensemble-aware validation frameworks for fit-to-data and uncertainty

📋 Requirements

  • Ph.D. in structural biology, biophysics, computational biology, or related field
  • Demonstrated expertise in structural biology methods
  • Deep understanding of structural heterogeneity and dynamics in biomolecular systems
  • Experience with data standards, metadata frameworks, or scientific database development

✨ Nice to Have

  • Experience with PDB, EMDB, BMRB, or other structural biology databases
  • Knowledge of validation methods for experimental and computational structural data
  • Familiarity with machine learning workflows and ML-ready data formats

🎁 Benefits & Perks

  • 💰 Competitive compensation package
  • 🏖️ Generous PTO
  • 🏥 Health insurance
  • 📈 Equity options
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