4h ago

Principal Scientist, Antibody Engineering & Rational Design

South San Francisco, CA

$198,000-$241,000 / year

full-timeseniorbiotechnology

Tech Stack

Description

You will bridge computational design and experimental validation in our antibody discovery engine. You'll serve as the primary liaison between wet-lab and ML teams, driving the Design-Build-Test-Learn cycle to enable rational, data-driven biologic drug discovery.

Requirements

  • Ph.D. in molecular biology, biochemistry, or related field
  • 8+ years post-PhD experience in antibody/protein engineering
  • Experience working with data scientists and ML engineers
  • Hands-on proficiency with structural modeling and ML protein design tools
  • Expert knowledge of antibody structure-function and rational design

Responsibilities

  • Serve as primary liaison between wet-lab antibody team and ML team
  • Drive Design-Build-Test-Learn cycle for antibody discovery
  • Translate computational designs into experimental workflows
  • Ensure computational predictions are validated and data retrains models
  • Champion rational, data-driven approach to biologic drug discovery
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