Tech Stack

Description

You will join a cross-functional team developing Natera's oncology product portfolio, designing and validating automated high-throughput NGS assays for clinical use. You'll investigate the feasibility of scientific principles in oncology diagnostics and collaborate with various internal groups to ensure quality standards. This role requires flexibility to work outside standard hours to support urgent projects and maintain lab operations.

Requirements

• BA/BS with 6 years experience or MS with 3 years experience in assay development and automation for genomics
• Demonstrated track record of development and validation of automated protocols for CLIA
• Strong understanding of chemistry underlying nucleic acid extraction, PCR, NGS library preparation, and hybrid capture technologies
• Hands-on experience in reagent preparation and quality control for NGS-based assays
• Experience implementing, optimizing, and troubleshooting high-throughput automated assays
• Data analysis (JMP) required
• Experience designing and executing studies including stability, guard banding, reproducibility and repeatability, and validation
• Experience working in a regulated laboratory environment under CLIA/CAP, NYSDOH, IVD is a plus
• Excellent communication, organizational, record-keeping, planning, attention to detail and time management skills
• Ability to collaborate cross-functionally

Responsibilities

• Design, develop, and validate automated high-throughput NGS assays
• Participate in post-launch surveillance by troubleshooting production issues
• Independently design and execute moderate to high complexity experiments
• Collaborate with assay development scientists on specifications
• Work with Clinical Laboratory and Quality Assurance to meet quality standards
• Coordinate across multiple internal groups
• Write documentation and SOPs, and train lab operations operators
• Oversee validation activities
• Identify areas for continuous improvement