18h ago

Associate Scientist II

San Carlos, CA

$106.1k-$116.5k / year

contractmidbiotech

๐Ÿ’ผ About This Role

You'll contribute to the development of a robust process for generating the company's proprietary pneumococcal conjugate vaccine. Your focus will be on synthesis, purification, and analytical characterization of chemically modified polysaccharides and polysaccharide-protein conjugates. This contract role offers hands-on experience in conjugation development within a clinical-stage biotech.

๐ŸŽฏ What You'll Do

  • Perform and optimize multi-step syntheses of protein-polysaccharide conjugates
  • Purify polysaccharides and conjugates using dialysis, SEC, and TFF
  • Analyze conjugates with colorimetric assays, HPLC, SEC-MALS, SDS-PAGE
  • Maintain experimental records and contribute to troubleshooting

๐Ÿ“‹ Requirements

  • BS degree in Chemistry, Biochemistry, or related field with 2+ years industry experience (or MS with 1+ year)
  • Experience with protein purification methods such as dialysis, diafiltration, and SEC
  • Working knowledge of analytical methods including colorimetric assays, HPLC, SEC, and SDS-PAGE

โœจ Nice to Have

  • Experience with TFF (tangential flow filtration)
  • Hands-on experience with protein conjugation reactions or chemical polysaccharide modification

๐Ÿ“จ Hiring Process

Estimated timeline: 2-3 weeks ยท AI estimate

  1. 1Recruiter screenยท 30 min
  2. 2Technical interviewยท 60 min
  3. 3Hiring manager interviewยท 45 min
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