20h ago
Staff Senior Scientist, Assay Development (Library Prep)
Berkeley, CA
โจ $120k-$160k / yearest.
full-timeseniorbiotech
๐ Tech Stack
๐ผ About This Role
You'll own the design and optimization of library preparation workflows for nanopore sequencing at a single-molecule proteome sequencing company. Your work will directly shape the future of protein sequencing, enabling transformative discoveries in life science.
๐ฏ What You'll Do
- Design and optimize end-to-end library preparation workflows for nanopore sequencing
- Develop characterization assays to monitor efficiency and construct integrity
- Investigate and resolve yield-limiting artifacts from protein sequencing assay chemistry
- Translate manual workflows to automated liquid handling platforms
๐ Requirements
- Advanced degree in Molecular Biology or related field with 6-8+ years relevant industry experience
- Deep understanding of enzymatic DNA manipulation including ligation, end repair, and polymerase extension
- Hands-on experience designing and troubleshooting NGS library preparation workflows
- Proficiency with capillary electrophoresis or gel-based QC methods
โจ Nice to Have
- Direct experience with Oxford Nanopore library preparation kits
- Experience with automated liquid handling platforms (Hamilton, KingFisher)
- Background in protein sequencing or proteomics sample preparation
๐ Benefits & Perks
- ๐ฐ Competitive salary and equity
- ๐๏ธ Flexible PTO
- ๐ฅ Health, dental, and vision insurance
- ๐ 401(k) plan
- ๐งช Opportunity to shape cutting-edge technology
๐จ Hiring Process
Estimated timeline: 2-4 weeks ยท AI estimate
- 1Recruiter Screenยท 30 min
- 2Technical Interviewยท 60 min
- 3Onsite Interviewยท 3-4 hours
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