20h ago
Associate Scientist II, Conjugation Development
San Carlos, California, United States
$106.1k-$116.5k / year
contractmidbiotech
💼 About This Role
You'll contribute to developing robust processes for pneumococcal conjugate vaccines, focusing on synthesis, purification, and analytical characterization of polysaccharide-protein conjugates. Your work will directly impact process optimization and help protect humankind from bacterial diseases. This role offers hands-on experience with cutting-edge vaccine technology at a clinical-stage company.
🎯 What You'll Do
- Perform and optimize multi-step syntheses of protein-polysaccharide conjugates
- Purify polysaccharides and conjugates using dialysis, SEC, and TFF
- Analyze conjugates by colorimetric assays, HPLC, SEC-MALS, and SDS-PAGE
- Maintain accurate experimental records and track critical reagent inventory
📋 Requirements
- BS in Chemistry or Biochemistry with 2+ years industry experience, or MS with 1+ year
- Experience with laboratory-scale protein purification methods like dialysis and SEC
- Working knowledge of analytical methods including HPLC, SEC, and SDS-PAGE
✨ Nice to Have
- Experience with TFF
- Hands-on experience with protein conjugation or polysaccharide chemical modification
📨 Hiring Process
Estimated timeline: 2-4 weeks · AI estimate
- 1Recruiter Screen· 30 min
- 2Hiring Manager Interview· 1 hour
- 3Technical Interview· 1 hour
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