Description

Lead nonclinical pharmacology strategy for oncology programs from discovery through IND submission. You will design and oversee in vivo PK/PD and efficacy studies, contribute to IND-enabling study design and regulatory filings, and integrate pharmacology data with other disciplines to inform development decisions.

Requirements

• PhD in Pharmacology, Biology, or related field with 8+ years post-degree experience
• 2+ years program leadership and people management experience
• Experience supporting first-in-class or novel mechanism oncology programs
• Experience with small molecules, peptides, degraders, or biologics
• Demonstrated success advancing program to development candidate nomination; IND submission experience required

Responsibilities

• Lead nonclinical pharmacology strategy for oncology programs from late discovery through IND
• Design, oversee, interpret, and communicate in vivo PK/PD and efficacy studies
• Contribute to IND-enabling study design and author pharmacology sections of regulatory submissions
• Integrate pharmacology data with DMPK, safety, and biomarker findings
• Present data and strategy updates to senior leadership and governance teams