🛠 Tech Stack

💼 About This Role

You'll lead conjugation process development for pneumococcal conjugate vaccines at a clinical-stage biotech. You'll optimize and scale polysaccharide-protein conjugation processes for pipeline programs. This lab-based role offers ownership of complex bioconjugation workflows from bench to tech transfer.

🎯 What You'll Do

• Optimize and troubleshoot multi-step syntheses of protein-polysaccharide conjugates
• Purify polysaccharides and conjugates using dialysis, SEC, and TFF
• Analyze conjugates with colorimetric assays, HPLC, and SEC-MALS
• Serve as subject matter expert during tech transfer to CMOs

📋 Requirements

• PhD in chemistry/biochemistry with 2+ years industry experience or equivalent
• Proficiency with bioconjugate purification including TFF
• Proficiency in bioconjugate analysis (colorimetric assays, HPLC, SEC-MALS)
• Strong organic chemistry knowledge for bioconjugate preparation

✨ Nice to Have

• Experience with Design of Experiments
• Experience with chemical modification of polysaccharides
• Experience using electronic notebooks

🎁 Benefits & Perks

• 💰 Competitive compensation including equity
• 🏥 Comprehensive benefits package
• 🏢 Onsite lab role in San Carlos, CA