8h ago
Senior Scientist, LNP Platform & Process Development
San Diego, CA
✨ $130k-$170k / yearest.
full-timeseniorbiotechnology
💼 About This Role
You'll lead the design and optimization of lipid nanoparticle (LNP) formulations for in vivo CAR-Treg delivery at a clinical-stage biotech startup. Your work will directly impact the manufacturability and scalability of the targeted LNP platform. This is a high-impact, foundational role where you'll influence both short-term execution and long-term strategy.
🎯 What You'll Do
- Design and optimize LNP formulations for mRNA delivery
- Evaluate lipid composition and formulation parameters
- Develop scalable, GMP-compatible manufacturing processes
- Lead analytical characterization method development
📋 Requirements
- Ph.D. with 4+ years or M.S. with 8+ years industry experience
- Hands-on expertise in LNP formulation and process development
- Experience with microfluidic mixing and downstream purification
- Strong background in analytical characterization of LNP systems
✨ Nice to Have
- Experience with mRNA therapeutics or nucleic acid delivery
- Prior exposure to immunotherapy or cell therapy platforms
- Familiarity with CMC regulatory expectations
🚩 Heads Up
- Position lists many preferred qualifications that may be unrealistic for a startup environment
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