8h ago

Senior Scientist, LNP Platform & Process Development

San Diego, CA

✨ $130k-$170k / yearest.

full-timeseniorbiotechnology

💼 About This Role

You'll lead the design and optimization of lipid nanoparticle (LNP) formulations for in vivo CAR-Treg delivery at a clinical-stage biotech startup. Your work will directly impact the manufacturability and scalability of the targeted LNP platform. This is a high-impact, foundational role where you'll influence both short-term execution and long-term strategy.

🎯 What You'll Do

  • Design and optimize LNP formulations for mRNA delivery
  • Evaluate lipid composition and formulation parameters
  • Develop scalable, GMP-compatible manufacturing processes
  • Lead analytical characterization method development

📋 Requirements

  • Ph.D. with 4+ years or M.S. with 8+ years industry experience
  • Hands-on expertise in LNP formulation and process development
  • Experience with microfluidic mixing and downstream purification
  • Strong background in analytical characterization of LNP systems

✨ Nice to Have

  • Experience with mRNA therapeutics or nucleic acid delivery
  • Prior exposure to immunotherapy or cell therapy platforms
  • Familiarity with CMC regulatory expectations

🚩 Heads Up

  • Position lists many preferred qualifications that may be unrealistic for a startup environment
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