23h ago

Senior Scientist, DMPK

Cambridge, MA

$130k-$150k / year

full-timeseniorbiotech

💼 About This Role

You'll lead non-clinical DMPK studies to advance transformative allosteric therapeutics from discovery to first-in-human trials. As a key scientific team member, you'll design ADME/PK strategies and collaborate cross-functionally to optimize preclinical models. This role offers a chance to contribute to an exciting early-stage biotech pipeline.

🎯 What You'll Do

  • Represent DMPK on preclinical project teams
  • Design and oversee in-vitro ADME/DMPK assays
  • Interpret DMPK data for structure-property relationships
  • Develop DMPK strategies for hit-to-lead and lead optimization

📋 Requirements

  • PhD in pharmacokinetics or related disciplines
  • 5+ years industry experience in drug development
  • Expertise in drug metabolism and pharmacokinetics
  • Experience managing CROs and GLP activities

✨ Nice to Have

  • Experience with regulatory submissions for small molecules
  • Experience in nonclinical toxicology
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