23h ago
Senior Scientist, DMPK
Cambridge, MA
$130k-$150k / year
full-timeseniorbiotech
💼 About This Role
You'll lead non-clinical DMPK studies to advance transformative allosteric therapeutics from discovery to first-in-human trials. As a key scientific team member, you'll design ADME/PK strategies and collaborate cross-functionally to optimize preclinical models. This role offers a chance to contribute to an exciting early-stage biotech pipeline.
🎯 What You'll Do
- Represent DMPK on preclinical project teams
- Design and oversee in-vitro ADME/DMPK assays
- Interpret DMPK data for structure-property relationships
- Develop DMPK strategies for hit-to-lead and lead optimization
📋 Requirements
- PhD in pharmacokinetics or related disciplines
- 5+ years industry experience in drug development
- Expertise in drug metabolism and pharmacokinetics
- Experience managing CROs and GLP activities
✨ Nice to Have
- Experience with regulatory submissions for small molecules
- Experience in nonclinical toxicology
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