10h ago

Principal Associate Scientist, Display Technologies

South San Francisco, California, United States

$110k-$138k / year

full-timeleadbiotech

🛠 Tech Stack

💼 About This Role

You'll join the Protein Engineering group to design and build complex DNA libraries for display technologies. Your work will directly enable AI-driven drug discovery by optimizing lead molecules.

🎯 What You'll Do

  • Design and apply phage, yeast, and mammalian display selections.
  • Utilize FACS sorting and NGS to identify binders.
  • Automate lead ranking for affinity and function.
  • Train and mentor junior team members.

📋 Requirements

  • BS/MS with 5+ years industrial experience in display/expression library building.
  • Hands-on experience with phage and/or yeast display to protein targets.
  • Proficiency in molecular biology techniques (PCR, DNA extraction, NGS library prep).
  • Experience with automation and FACS (analytical and sorting).

✨ Nice to Have

  • Experience in protein purification (affinity, ion exchange, SEC).
  • Familiarity with LIMS and Benchling systems.

🎁 Benefits & Perks

  • 💰 Competitive base salary ($110k-$138k)
  • 📈 Equity and bonus included in compensation package
  • 🏖️ Open, flexible work environment
  • 🌱 Career development platform
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