10h ago
Principal Associate Scientist, Display Technologies
South San Francisco, California, United States
$110k-$138k / year
full-timeleadbiotech
🛠 Tech Stack
💼 About This Role
You'll join the Protein Engineering group to design and build complex DNA libraries for display technologies. Your work will directly enable AI-driven drug discovery by optimizing lead molecules.
🎯 What You'll Do
- Design and apply phage, yeast, and mammalian display selections.
- Utilize FACS sorting and NGS to identify binders.
- Automate lead ranking for affinity and function.
- Train and mentor junior team members.
📋 Requirements
- BS/MS with 5+ years industrial experience in display/expression library building.
- Hands-on experience with phage and/or yeast display to protein targets.
- Proficiency in molecular biology techniques (PCR, DNA extraction, NGS library prep).
- Experience with automation and FACS (analytical and sorting).
✨ Nice to Have
- Experience in protein purification (affinity, ion exchange, SEC).
- Familiarity with LIMS and Benchling systems.
🎁 Benefits & Perks
- 💰 Competitive base salary ($110k-$138k)
- 📈 Equity and bonus included in compensation package
- 🏖️ Open, flexible work environment
- 🌱 Career development platform
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