Careers | Nuvalent

You will assess and interpret safety data from clinical trials, spontaneous reports, and literature, contributing to aggregate safety reports, signal detection, and risk management plans. You'll collaborate with cross-functional teams and CROs to ensure regulatory compliance and patient safety.

You'll maintain the validation lifecycle of GxP-regulated computerized systems in a remote pharmaceutical operating model. You'll partner cross-functionally to support system implementations and ensure regulatory compliance. This role offers the chance to shape validation practices for an innovative early-stage oncology company.

You'll provide vendor oversight and review of ICSR processing for a **selective medicines company** focused on cancer patients. Your core impact is ensuring compliance and data quality from the **Global Safety Database**. This role offers the chance to shape PV operations as the company approaches market authorization.

You'll manage vendor oversight and ICSR processing for investigational products in a **clinical-stage biotech company**. You'll ensure regulatory compliance and data integrity across Phase 1-3 studies. This role offers direct impact on **safety operations strategy**.

You will lead statistical programming activities for clinical trials, producing and validating tables, listings, figures, and analysis datasets. You'll collaborate with cross-functional teams and oversee CROs to ensure accurate, regulatory-compliant data outputs.

You'll manage the analytical Reference Material Reference Standards program, ensuring compliance with cGxP for clinical and commercial operations. You'll lead **reference material lifecycle management** and coordinate **commercial readiness deliverables** for fast-paced development programs. This role offers a chance to work in a **virtual environment** supporting oncology drug development.

You'll **spearhead thought leader engagement** for Nuvalent's oncology launch, developing and executing a comprehensive commercial strategy for lung cancer KOLs. You'll collaborate with cross-functional teams to **capture competitive insights** and manage key account relationships. This role offers the chance to **shape launch readiness** at a fast-growing biopharma company.

You will lead payer marketing, organized customer marketing, and patient support services marketing to ensure payer coverage and patient access for upcoming launches in NSCLC. Collaborating cross-functionally with Sales, HEOR, and Medical Affairs, you will develop compelling value propositions, manage agency partners, and create training materials to drive launch readiness and post-launch success.

You'll join an early-stage oncology company leading **analytical method development** for drug products. Your core impact will be driving phase-appropriate analytical strategies and managing CRO/CDMO relationships. This role offers the chance to work on **novel small molecule therapies** in a fast-paced cross-functional environment.

You will ensure excellence in clinical trial planning, execution, and data collection in accordance with regulatory guidelines at Nuvalent, an early-stage oncology biotech. You'll manage site selection, contracts, budgets, and vendor partnerships to deliver high-quality clinical trial results.

You will lead the DMPK strategy across the company, overseeing studies to support discovery, development, and regulatory filings. You'll build and guide a high-performing team, collaborate cross-functionally, and ensure high-quality data for IND, CTA, and NDA submissions. This is a pivotal role in a fast-growing biotech preparing for its first commercial launch.

You will lead the clinical pharmacology strategy across all development programs, including late-stage registrational efforts and early-phase assets. Your work will guide dose optimization, exposure-response modeling, regulatory strategy, and NDA submission components to address the needs of patients with cancer.

You'll lead **medical assessment of safety data** for novel cancer therapies, collaborating with cross-functional teams to ensure regulatory compliance and patient safety. You'll shape **safety surveillance strategies** and contribute to regulatory submissions. This role offers the chance to impact early-stage drug development at a **highly innovative biotech**.