Jobs at Profluent

You'll own full-cycle recruiting and strengthen people operations for an AI-first protein design company. You'll focus on talent acquisition while building an employee experience that enables people to thrive. This role offers the chance to **shape team and culture** during a **pivotal growth stage**.

You'll build and operate infrastructure for large-scale ML systems at an AI-first protein design company. You'll enable machine learning scientists to quickly move from experiments to production models, with significant ownership as an early member. This role offers the chance to work on **cutting-edge generative biology models** and **massive biological datasets**.

You'll design, validate, and execute high-throughput experiments to characterize and optimize therapeutic gene editing proteins for an AI-first protein design company. Your work will be foundational for expanding our gene editing toolbox. This is an excellent opportunity to work cross-functionally with experts in machine learning, protein design, and cell biology.

You'll own Profluent's **security posture** across scientific systems, lab automation, and cloud infrastructure, designing and implementing technical controls and compliance frameworks. Your work will directly enable **SOC 2 certification** and protect data in an AI-first protein design company. This role offers broad ownership beyond typical infrastructure or compliance positions.

You'll **maintain automation equipment** and support **high-throughput molecular cloning and screening workflows** for an AI-first protein design company. Your work will directly accelerate discoveries in biomedicine.

You'll optimize **LNP delivery systems** for **AI-designed gene editors**, transitioning them from bench to in vivo. Your core impact will be formulating and characterizing LNPs for preclinical studies. This role offers a chance to work at the **intersection of AI and biology** in a well-funded startup.

You'll drive research into **reinforcement learning for biomolecular design** at an AI-first protein design company. Your work will directly impact the development of **novel functional proteins** to revolutionize biomedicine. This role offers an opportunity to pioneer at the intersection of **generative modeling and protein engineering**.

You'll **establish experimental workflows** for **CRISPR base editor specificity assessment** at an AI-first protein design company. Your work will generate **decision-quality datasets** that guide editor design and therapeutic development. This role offers the opportunity to shape how AI-designed genome editing systems are evaluated.

You'll lead **in vivo pharmacology strategy** for **AI-designed gene editing therapeutics** at a well-funded biotech startup. Your core impact is generating decision-quality preclinical data to guide candidate selection and IND-enabling plans. This role offers the chance to **build the in vivo pharmacology function** from the ground up.

You'll design **state-of-the-art generative models** for **protein engineering** at a well-funded AI-first biotech. Your work will directly shape the company's ML direction and accelerate drug discovery.

You'll lead **end-to-end mRNA production workflows** for customized base editor programs at an **AI-first protein design company**. Your work will directly enable high-throughput screening and **preclinical in vivo studies** by delivering high-quality RNA materials.

You'll join moonshot projects at the intersection of **bioinformatics** and **machine learning**, analyzing large-scale genomic and protein datasets. Your work will have direct potential for **high-impact publications** and real-world applications in synthetic biology.

You'll lead the design and operation of the NGS analysis platform powering Profluent's **gene editing** and **protein design** programs. Your work will directly accelerate design-build-test-learn cycles. This role offers a unique opportunity at the intersection of **AI and biology**.

You'll join an AI-first protein design company to design and optimize high-throughput screening campaigns for novel gene editing tools. Your work will be critical for enabling new therapeutic opportunities. This role offers exposure to **cutting-edge AI and biology** and a chance to work with a **diverse team of experts**.

You'll own the development and deployment of **agentic workflows for protein design**, building automated pipelines that connect computational models with wet-lab validation. You'll work across the full stack to integrate protein language models, structure predictors, and experimental feedback into robust systems. This is a high-ownership role at a well-funded AI-first startup.

You'll lead **legal strategy and execution** for complex **business development transactions** at an AI-first protein design company. You'll serve as a **true thought partner** to BD and executive leadership, shaping deals from conception to close.

You'll lead a team building scientist-facing tools for experiment design, sample tracking, and assay data capture at an AI-first protein design company. Your work will **accelerate the design-build-test-learn cycle** for novel protein therapies. This role offers **deep involvement in architecture and data modeling** alongside people management.

You'll design, build, and scale Profluent's data platform for protein engineering campaigns. Your work will enable rapid machine learning and biological discovery by creating secure, well-structured data systems. You'll collaborate with ML, bioinformatics, and program teams to ensure data is **organized, governed, and accessible**.