Astera Institute

You'll coordinate efforts across a **multidisciplinary scientific team** spanning wet-lab, computational, and ML research. You'll ensure **strategic alignment** and clear communication across partner institutions.

You'll architect high-performance infrastructure for **brain-inspired AI models** at a well-funded research foundation. You'll **reverse-engineer neural systems** by building custom RL environments and production-grade code. This role offers **unprecedented compute resources** and freedom from funding pressures.

You'll architect high-performance infrastructure for large-scale model training and custom RL environments at a neuroscience-focused AI research organization. Your work will directly unblock the research team by solving critical technical bottlenecks. This role offers the chance to work on ambitious AGI goals with unprecedented computational resources.

You'll build and run a **rodent neuroscience program**, performing surgeries like cranial window implants and handling colony management. You'll enable **high-resolution functional imaging** studies for a team of scientists. This role offers **hands-on work with cutting-edge tools** in a growing company.

You'll develop **energy-based hierarchical latent variable models** and **learning/inference algorithms** for neuroscience-inspired world models. You'll bridge biological intelligence, computational theory, and building at scale. This role offers **high autonomy** with no pressure to align research with quarterly revenue goals.

You'll develop **foundational principles of AGI** by bridging biological intelligence and computational theory. Your work will directly influence **safe development of AGI** with high autonomy. You'll collaborate with neuroscientists and engineers to **translate abstract frameworks into scalable systems**.

You'll own the digital infrastructure powering a neuroscience-informed AGI research program. You'll ensure reliable access to compute resources, cluster health visibility, and auto-scaling. This role offers the chance to work on **ambitious goals** at a high-velocity startup foundation.

You'll co-architect Radial's scientific and technical direction, building **AI and computational infrastructure** across programs. You'll personally drive early prototypes and set the technical bar through **hands-on work**. This role offers a chance to shape foundational bottlenecks in life science research.

You'll lead the vision, strategy, and execution of **The Stacks**, a new open-access platform for scientific knowledge. You'll drive product development from concept to launch, collaborating closely with engineering and design to shape **an innovative research tool**. This role offers the chance to **champion open science** and make a tangible impact on how research is shared and discovered.

You'll develop foundational principles of Artificial General Intelligence by bridging biological intelligence, computational theory, and scalable systems. You'll conduct **fundamental research on brain-like world models** and **design experiments** to test hypotheses about cognition. This role offers **high autonomy** and a direct impact on AGI breakthroughs.

You'll join Astera Institute to develop **new architectures** for data-efficient model induction, including **bootstrapped program synthesis** and **machine learning strange loops**. Your work will help overcome barriers in small, heterogeneous datasets common in science.

You'll develop foundational principles of **Artificial General Intelligence** by bridging biological intelligence and computational theory. You'll design and implement **hierarchical RL algorithms** for world model learning and planning. This role offers **high autonomy** and a direct impact on AGI research, with no pressure to align with quarterly revenue goals.

You'll help **reverse-engineer the human brain** by architecting high-performance infrastructure for large-scale models and simulations. You'll design **custom RL environments** informed by neuroscience and turn research prototypes into **scalable production systems**. This role offers the chance to tackle ambitious AGI goals with unprecedented resources.

You'll apply **X-ray crystallography** to study protein dynamics within the multi-institution diffUSE Project. Your work will uncover hidden information from diffuse scattering data to **visualize protein motions**. You'll collaborate across experimental, computational, and theoretical teams in an open-science environment.

You'll develop a **rigorous theory of latent internal structure** in neural networks at a mission-driven startup. Your work will directly inform **AI safety** by uncovering belief geometries and generalization mechanisms. You'll collaborate across fields like physics, neuroscience, and machine learning.

You'll lead the development of standards and platforms for a dynamic structural biology database, working at the intersection of structural biology, data science, and community standards. Your core impact will be building an ensemble-aware, living database that makes dynamic structural biology data as accessible and trustworthy as the PDB. This role stands out for operating at a high-velocity, startup-like research foundation.

You'll lead development of a **miniaturized two-photon microscope** for simultaneous imaging and holographic photostimulation in rodents. Your work will enable **all-optical readout and perturbation** of neural circuits at single-cell resolution. You'll enjoy **institutional support** to move fast on transformative neuroscience.

You'll build core infrastructure for **large-scale distributed simulation systems**, including biological and 3D physics environments. Your work will enable synchronized multi-node simulation at the intersection of **distributed computing** and **high-performance C++**. This role offers an opportunity to tackle ambitious goals in a high-velocity, startup-like research environment.

You'll contribute to **distributed simulation infrastructure** for a **private foundation** driving scientific and technological abundance. You'll help build systems for biological and physics-based simulations, working with experienced engineers on real technical problems in a high-velocity startup-like environment.

You'll analyze large-scale connectome and neurophysiology datasets and develop **computational models of neural circuits**. You'll collaborate with researchers to interpret experimental data and implement **data analysis pipelines**. This internship offers exposure to high-velocity research operations at a private foundation.

You'll design and execute experiments using **in vitro brain slice prep** to characterize complex neuronal networks. Your work will directly impact **neurotechnology development** at the intersection of stem cell biology and quantitative neuroscience. You'll join a **high-velocity research environment** focused on ambitious scientific goals.

You'll join a growing team building **open infrastructure** for studying **protein dynamics** from experimental data. Your work will directly impact structural biology, machine learning, and open science. This role offers the chance to shape a new project at a **mission-driven institute**.